Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC541H871N145O166S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISGIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRSMVHISKVFVTAIFSTPLDNTDPASISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12190.83 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.22

Net Charge (pH 7.4) 0.97

Charge Density (pH 7.0) 0.0107

GRAVY Index0.08

Hydrophobic Moment 0.60

Boman Index0.14

Instability Index24.67

Aliphatic Index 97.46

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4951.24

LogP -55.33

H-bond Donors 175.0

H-bond Acceptors 174.0

Rotatable Bonds 403.0

Heavy Atoms 856.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008109 VERIFIED: NO

Provenance & Taxonomy

OrganismCalyptomena viridis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria