Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC404H632N116O114S

DescriptionStandard

        MSQNPELIAQFSSGNQTRIKQGLTAKAPIDGWYYGPKEIVKKFQIHHRVAIEYGGEVYDIGNLRIVTPRLRDEIHYGR
    

Molecular Weight8970.11 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)2.77

Net Charge (pH 7.4) 2.38

Charge Density (pH 7.0) 0.0355

GRAVY Index-0.59

Hydrophobic Moment 0.54

Boman Index-0.06

Instability Index44.89

Aliphatic Index 85.00

Aromaticity 0.1026

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 12950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3737.84

LogP -33.25

H-bond Donors 129.0

H-bond Acceptors 121.0

Rotatable Bonds 298.0

Heavy Atoms 635.0

Ring Count 16.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384095 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal