Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Standard StatusStandard

Sequence Length558 amino acids

Chemical FormulaC2630H4154N786O822S22

DescriptionStandard

        MGNRSDCYGRGTALEGDKTTTGAVCIASMSNDTEHGRRVMRVGDKTTRCLKCGEPGVVVSGEPRDTNMGKIAAVDGSIVRCACPSGSNRIIAPAGQWVGPGEDPSIAARAQLFAERKAAQEAEEKRRAEEQERNRVFAKSCLRGEGCNDAGTQQEPHTNFADMGLFKAAPATDAATDSDAPQHAQTAKKKPPAPEDIPKPKKRSVLYKWLNGNHEEMEYQAAVAAAASATRVQTATAGVNVLEQIGGRFATYGTWAVRGAEIATAGAGASVAGFLVGMMPGRLNDGEQDFIDRMRLAQMSEAPTRVRYTWENDSNGNPVPHGWHTPPGKDMVRVRKMQWDSTRQAYTFTTEEESPVIIIWTPDHSGANTPTNTGNQTPPRLPGTILVNPLPDGTQITSTTTPAPDEKNFADYILILPVSDIPPIYIYIRNNPGQVTGKGQKVTGTWLADANQGNGSPIPSQIADKLRGRTFSNFDGFREAFWEEVSKDSELLKQFIPGNLARMKYGLSPRTRFVDTVGKRRSFEIHHIKPVSQGGDLYNVDNMGITTPKRHIDVHRGT
    

Molecular Weight60641.32 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)3.47

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0062

GRAVY Index-0.61

Hydrophobic Moment 0.86

Boman Index-0.08

Instability Index34.87

Aliphatic Index 62.83

Aromaticity 0.0645

Extinction Coeff. Reduced 65890.00

Extinction Coeff. Oxidized 66390.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164849 VERIFIED: NO

Provenance & Taxonomy

OrganismLeclercia sp. 29361 [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase

TargetEscherichia coli