Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC192H298N56O62S7

DescriptionStandard

        CPGEAQGPDSCNHGGGLCRVGSCVSGEYLAQYCFEPVILCCRNL
    

Molecular Weight4607.21 Da

Isoelectric Point (pI)4.83

Net Charge (pH 7.0)-2.21

Net Charge (pH 7.4) -2.58

Charge Density (pH 7.0) -0.0503

GRAVY Index0.08

Hydrophobic Moment 0.46

Boman Index0.12

Instability Index42.04

Aliphatic Index 68.64

Aromaticity 0.0682

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1863.44

LogP -23.11

H-bond Donors 69.0

H-bond Acceptors 68.0

Rotatable Bonds 144.0

Heavy Atoms 317.0

Ring Count 7.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153377 VERIFIED: YES

Provenance & Taxonomy

OrganismPasser domesticus [Animal]

FamilyDefensin

Tax ID48849

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/

RECORD: Rec_0218309 VERIFIED: NO