Peptide Database

Peptide NameCathelicidin-2 (CATH-2) (Fowlicidin-2) (Myeloid antimicrobial peptide 27)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC748H1209N215O219S8

DescriptionStandard

        MLSCWVLLLALLGGVCALPAPLSYPQALIQAVDSYNQRPEVQNAFRLLSADPEPGPGVDLSTLRALNFTIMETECTPSARLPVDDCDFKENGVIRDCSGPVSVLQDTPEINLRCRDASSDPVLVQRGRFGRFLRKIRRFRPKVTITIQGSARFG
    

Molecular Weight16974.43 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 1.14

Charge Density (pH 7.0) 0.0095

GRAVY Index-0.04

Hydrophobic Moment 1.06

Boman Index0.00

Instability Index44.53

Aliphatic Index 95.58

Aromaticity 0.0649

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6942.18

LogP -70.75

H-bond Donors 245.0

H-bond Acceptors 229.0

Rotatable Bonds 549.0

Heavy Atoms 1190.0

Ring Count 24.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254949 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyCathelicidin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria

RECORD: Rec_0290014 VERIFIED: NO