Peptide Database

Peptide NamePeptide PP4-3.1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC94H169N23O20

DescriptionStandard

        KTTKSKKLLKWLLKLL
    

Molecular Weight1941.49 Da

Isoelectric Point (pI)10.70

Net Charge (pH 7.0)5.75

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.3596

GRAVY Index-0.23

Hydrophobic Moment 0.74

Boman Index-0.13

Instability Index-4.14

Aliphatic Index 146.25

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 732.42

LogP -1.80

H-bond Donors 27.0

H-bond Acceptors 26.0

Rotatable Bonds 72.0

Heavy Atoms 137.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365861 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStreptococcus pyogenes ATCC 19615

Activity2.7 μg/mL

MethodMIC

RECORD: Rec_0404192 VERIFIED: YES