Peptide Database

Peptide NameDefensin alpha 24

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC438H721N121O137S8

DescriptionStandard

        MKTLVLLSALVLLALQVQAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRAKSCNWGEGIMGICNKRYGSLILCCR
    

Molecular Weight10130.66 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0166

GRAVY Index-0.11

Hydrophobic Moment 0.78

Boman Index0.01

Instability Index33.30

Aliphatic Index 91.18

Aromaticity 0.0430

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4165.74

LogP -43.08

H-bond Donors 147.0

H-bond Acceptors 144.0

Rotatable Bonds 344.0

Heavy Atoms 704.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301109 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0346940 VERIFIED: NO

Provenance & Taxonomy

OrganismRanitomeya imitator [Animal]

Tax ID111125

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal