Peptide Database

Peptide NameMesotocin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC43H67N11O13S2

DescriptionStandard

        CYIQNCPIG
    

Molecular Weight1010.19 Da

Isoelectric Point (pI)5.51

Net Charge (pH 7.0)-0.26

Net Charge (pH 7.4) -0.49

Charge Density (pH 7.0) -0.0290

GRAVY Index0.41

Hydrophobic Moment 0.11

Boman Index0.29

Instability Index27.09

Aliphatic Index 86.67

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 393.74

LogP -3.54

H-bond Donors 14.0

H-bond Acceptors 15.0

Rotatable Bonds 29.0

Heavy Atoms 69.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057967 VERIFIED: NO

Provenance & Taxonomy

OrganismRana esculenta [Animal]; Taricha granulosa [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0075903 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0093355 VERIFIED: NO

Provenance & Taxonomy

OrganismBufo japonicus [Animal]

FamilyVasopressin/oxytocin

Tax ID8387

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Neurohypophyseal hormone Neuropeptide

RECORD: Rec_0192778 VERIFIED: YES

Provenance & Taxonomy

OrganismBufo japonicus [Animal]

FamilyMesotocin

Tax ID8387

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour