Peptide Database

Peptide NameDefensin alpha 5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC522H831N149O166S7

DescriptionStandard

        MRTLAFLAAALLLLALQANAKSLRETDDQVPAQDLPEALDQEQLEAEDQNQPGAKGQDVAISFGAPNRLVQGASGLRRITVCYCRSNFCSSPEVYSGTCTFNGIRYFLCCQ
    

Molecular Weight12074.54 Da

Isoelectric Point (pI)4.76

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.87

Charge Density (pH 7.0) -0.0319

GRAVY Index-0.12

Hydrophobic Moment 0.62

Boman Index0.01

Instability Index44.29

Aliphatic Index 85.41

Aromaticity 0.0721

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5103.11

LogP -58.57

H-bond Donors 178.0

H-bond Acceptors 170.0

Rotatable Bonds 398.0

Heavy Atoms 844.0

Ring Count 13.0

Amide Bonds 125.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169656 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinolophus ferrumequinum [Animal]

FamilyDefensin

Tax ID59479

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal