Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length426 amino acids

Chemical FormulaC2110H3336N534O625S14

DescriptionStandard

        ITARQQGIIVLQQKLSTIRLPDYSGSYSVGALGNVKYNINSMVITNFQLPNSQVTLLPNVGLKLSISGAYIEVHGRWGVRYLFISSDGDFELKVLGISVSVGLGLGSDGSGRPTISSSDCSANIADMQVHFSGGLDWLINLFDDQIASSLRDTMQNQICTQVNEAVKNQLEPVLRSLPVTSKIDDVASIDYSLMGPPIVSADYLDVQLKGEFFEQSQRTPPPFSPQPLSVPDDHNLMAYFAVSDYLFNTAVFVYQSAGKLIFNVTDDMIPKDFPVRLNTSSFGKMIPQISKMYPDMLMKLKISSPSAPFLTMKPENVTISPVLDIQAYAICPNSSLAPLFLLNLSADAVAKVGVNSSRIVGYLELSSIKIDLKQSDVGPFPVEILNFAVNYYISHILLPKINEILKNGYPLPLLDHIQLSNVSKAK
    

Molecular Weight46633.17 Da

Isoelectric Point (pI)5.42

Net Charge (pH 7.0)-5.81

Net Charge (pH 7.4) -6.40

Charge Density (pH 7.0) -0.0136

GRAVY Index0.12

Hydrophobic Moment 0.66

Boman Index0.15

Instability Index40.19

Aliphatic Index 105.89

Aromaticity 0.0845

Extinction Coeff. Reduced 34840.00

Extinction Coeff. Oxidized 34965.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279624 VERIFIED: NO

Provenance & Taxonomy

OrganismRanitomeya imitator [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria