MYP_067998
Brevinin-1HY
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
▸
Antifungal
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Standard
21 amino acids
C113H187N27O25S2
Standard
FALGAVTKVLYKLFCLITRKC
2387.99 Da
9.70
3.74
3.50
0.1779
1.10
0.63
0.27
2.52
130.00
0.1429
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
845.97
-2.99
33.0
31.0
79.0
167.0
3.0
20.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0344957
VERIFIED: YES
Provenance & Taxonomy
skin secretion of Amolops hainanensis [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
Horse blood cells: The haemolysis at the MIC of Brevinin-1HY (28.48%) was more than threefold at the MIC for the parent peptide
RECORD: Rec_0360458
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Staphylococcus aureus NCTC 10788
8 μM
MBC
RECORD: Rec_0385228
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Human breast adenocarcinoma MDA-MB-435S
2.243 μM
IC50
Showing 3 records on this page · Page 5 of 5