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MYP_067895
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Basic Information
Chensinin-1 (4-13) [ G4,7,11W, L12H ]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C78H103N29O11
Standard
Sequence
WRHWRRFWHR
Physicochemical Analysis
1622.84 Da
12.00
3.93
3.63
0.3934
-2.43
0.93
-0.73
106.34
0.00
0.4000
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
677.55
-1.84
28.0
17.0
47.0
118.0
9.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019541 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus cereus AS1.126
6.25 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0027389 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA
Hemolysis
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0070792 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
500 μM
HC50
PaperStructure-activity analysis and biological studies of chensinin-1b analogues. Acta Biomater. 2016 Jun;37:59-68. doi: 10.1016/j.actbio.2016.04.003. PMID: 27060618. PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0073325 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Lactococcus lactis AS1.1690
6.25 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0075521 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis CGMCC 1.595
3.13 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
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