Peptide Database

Peptide NameT-266

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC163H280N46O58

DescriptionStandard

        ISLERLDVGTNLGNAIAKLEDAKELLESSDQILRS
    

Molecular Weight3812.24 Da

Isoelectric Point (pI)4.44

Net Charge (pH 7.0)-3.23

Net Charge (pH 7.4) -3.44

Charge Density (pH 7.0) -0.0922

GRAVY Index-0.19

Hydrophobic Moment 0.65

Boman Index-0.04

Instability Index35.79

Aliphatic Index 128.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1720.08

LogP -18.64

H-bond Donors 59.0

H-bond Acceptors 55.0

Rotatable Bonds 136.0

Heavy Atoms 267.0

Ring Count 0.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356612 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic Anticancer

TargetNo significant cytotoxic against HEp2 cells

Activity100 μM

MethodCC50

RECORD: Rec_0377785 VERIFIED: YES