Peptide Database

Peptide NamePeptidyl-prolyl cis-trans isomerase A

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral budding inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length165 amino acids

Chemical FormulaC802H1236N218O237S9

DescriptionStandard

        MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
    

Molecular Weight18012.30 Da

Isoelectric Point (pI)7.68

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.31

Charge Density (pH 7.0) 0.0051

GRAVY Index-0.32

Hydrophobic Moment 0.70

Boman Index0.04

Instability Index10.65

Aliphatic Index 61.45

Aromaticity 0.1091

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7299.78

LogP -76.17

H-bond Donors 253.0

H-bond Acceptors 251.0

Rotatable Bonds 605.0

Heavy Atoms 1266.0

Ring Count 29.0

Amide Bonds 176.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176652 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCyclophilin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Bio-Activity Profile

Function

Antiviral Replication inhibitor Anti-IAV

TargetInfluenza A virus(IAV)

RECORD: Rec_0331799 VERIFIED: YES