Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC750H1176N222O218S6

DescriptionStandard

        MARVQFKQRESTDAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEEGRDEMAVGSHAKGHNHNSIGVCLVGGIDDKGKFEANFTPAQMKSLRSLLVTLLAKYEGAVLKAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16983.11 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.19

Net Charge (pH 7.4) 2.48

Charge Density (pH 7.0) 0.0211

GRAVY Index-0.53

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index39.53

Aliphatic Index 74.24

Aromaticity 0.0795

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7107.72

LogP -70.97

H-bond Donors 250.0

H-bond Acceptors 235.0

Rotatable Bonds 573.0

Heavy Atoms 1196.0

Ring Count 28.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038530 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoP_PHB19 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic