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MYP_067711
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Basic Information
Desotamide B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
6 amino acids
C34H52N8O8
Standard
Sequence
WLLVNG
Physicochemical Analysis
700.83 Da
5.53
-0.24
-0.44
-0.0400
1.17
0.15
0.62
3.85
178.33
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
267.70
-0.20
9.0
8.0
20.0
50.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0329101 VERIFIED: YES
Provenance & Taxonomy
Streptomyces nov. sp.,Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Mycobacterium bovis BCG
PMID25229313;29431987;25072108;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25229313/
RECORD: Rec_0361442 VERIFIED: YES
Provenance & Taxonomy
Streptomyces nov. sp.,Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus pneumoniae NCTC 7466
12.5 μg/mL
MIC
PMID25229313;29431987;25072108;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25229313/
RECORD: Rec_0368269 VERIFIED: YES
Provenance & Taxonomy
Streptomyces nov. sp.,Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella typhimurium CMCC 50097
128 μg/mL
MIC
PMID25229313;29431987;25072108;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25229313/
RECORD: Rec_0375598 VERIFIED: YES
Provenance & Taxonomy
Streptomyces nov. sp.,Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 10145
30 μM
IC50
PMID25229313;29431987;25072108;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25229313/
RECORD: Rec_0385929 VERIFIED: YES
Provenance & Taxonomy
Streptomyces nov. sp.,Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human breast adenocarcinoma MCF-7
268.5 μM
IC50
PMID25229313;29431987;25072108;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25229313/
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