Peptide Database

Peptide NameSLAY-screened peptide P40

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC44H74N16O19

DescriptionStandard

        SGSSPRNTQTP
    

Molecular Weight1131.15 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.25

Charge Density (pH 7.0) 0.0418

GRAVY Index-1.72

Hydrophobic Moment 0.22

Boman Index-0.37

Instability Index56.34

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 585.97

LogP -11.97

H-bond Donors 20.0

H-bond Acceptors 20.0

Rotatable Bonds 33.0

Heavy Atoms 79.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268348 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/