Peptide Database

Peptide NameRMeuTXKbeta1 truncated derivative C(22-72)

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC250H379N67O71S7

DescriptionStandard

        TVLQTVVHKVGKTQFGCPAYQGYCDDHCQDIEKKEGFCHGFKCKCGIPMGF
    

Molecular Weight5683.54 Da

Isoelectric Point (pI)7.55

Net Charge (pH 7.0)0.60

Net Charge (pH 7.4) 0.15

Charge Density (pH 7.0) 0.0118

GRAVY Index-0.31

Hydrophobic Moment 0.57

Boman Index0.04

Instability Index31.17

Aliphatic Index 47.65

Aromaticity 0.1176

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2202.91

LogP -20.92

H-bond Donors 79.0

H-bond Acceptors 82.0

Rotatable Bonds 187.0

Heavy Atoms 395.0

Ring Count 11.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075252 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyRMeuTXKbeta1 truncated

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antimalarial

TargetPlasmodium berghei ANKA 2.34

Activity20 μM

MethodPercent inhibition; Microscopy (Giemsa staining)

RECORD: Rec_0082563 VERIFIED: YES