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MYP_067662
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Basic Information
Arenicin-3 [Y5N,Y9R,Y17H], NZ17143
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C104H168N42O25S4
Standard
Sequence
GFCWNVCVRRNGVRVCHRRCN
Physicochemical Analysis
2534.97 Da
10.45
4.81
4.50
0.2289
-0.40
0.64
-0.33
91.88
55.24
0.0952
5500.00
5750.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1128.56
-13.42
46.0
35.0
81.0
175.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071522 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
0.25 μg/mL
MIC
PMID32576824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32576824/
RECORD: Rec_0117411 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae BAA-2146 NDM-1
4 μg/mL
MIC
PaperAn amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria.
RECORD: Rec_0195317 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ATCC 25922
0.25 μg/mL
MIC
PMID32576824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32576824/
RECORD: Rec_0273380 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells (50% Cell death at >300 microg/ml
293 μg/mL
Hemolysis
PMID32576824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32576824/
RECORD: Rec_0280973 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
300 μg/mL
Hemolysis
PMID32576824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32576824/
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