Peptide Database

Peptide NameInterleukin-1 beta

Function Ontology

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC773H1219N201O237S8

DescriptionStandard

        APVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS
    

Molecular Weight17376.67 Da

Isoelectric Point (pI)5.91

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0073

GRAVY Index-0.50

Hydrophobic Moment 0.65

Boman Index-0.04

Instability Index56.62

Aliphatic Index 75.10

Aromaticity 0.0915

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7135.78

LogP -71.25

H-bond Donors 238.0

H-bond Acceptors 245.0

Rotatable Bonds 593.0

Heavy Atoms 1219.0

Ring Count 24.0

Amide Bonds 173.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090748 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-1 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytokine Growth factor IL-1 family Chemokine-like Growth factor signaling Angiogenic