Peptide Database

Peptide NameHost defense peptide esculentin-2-RA2

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC371H627N97O115S5

DescriptionStandard

        MLTSKKSLLLLFFLGTISLSLCQEERAADEEDNGEVEEVKRGIFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC
    

Molecular Weight8446.85 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0065

GRAVY Index0.08

Hydrophobic Moment 0.67

Boman Index0.06

Instability Index17.59

Aliphatic Index 105.13

Aromaticity 0.0385

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3446.96

LogP -31.98

H-bond Donors 122.0

H-bond Acceptors 120.0

Rotatable Bonds 302.0

Heavy Atoms 588.0

Ring Count 3.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085102 VERIFIED: NO

Provenance & Taxonomy

OrganismOdorrana margaretae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence