Peptide Database

Peptide NameDefensin alpha 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC469H740N132O156S8

DescriptionStandard

        MRTLIFLAAILLVALKAQAEPLQAEDEPLQASTYEADAQEQRGADNQDFTISFTADANSSIRALGSTRSFTCNCRRSCYSTEYSYGTCTVMGVSNRFCCL
    

Molecular Weight10980.20 Da

Isoelectric Point (pI)4.73

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.87

Charge Density (pH 7.0) -0.0354

GRAVY Index-0.12

Hydrophobic Moment 0.57

Boman Index-0.00

Instability Index46.62

Aliphatic Index 72.40

Aromaticity 0.0900

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4692.45

LogP -58.17

H-bond Donors 171.0

H-bond Acceptors 161.0

Rotatable Bonds 361.0

Heavy Atoms 765.0

Ring Count 11.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190729 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence