Peptide Database

Peptide Name[G1K, K8R]cGm (Derived from Gm)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC94H162N38O23S4

DescriptionStandard

        KCRRLCYRQRCVTYCRGR
    

Molecular Weight2320.79 Da

Isoelectric Point (pI)10.33

Net Charge (pH 7.0)6.72

Net Charge (pH 7.4) 6.45

Charge Density (pH 7.0) 0.3732

GRAVY Index-1.12

Hydrophobic Moment 0.44

Boman Index-0.74

Instability Index28.95

Aliphatic Index 37.78

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1059.22

LogP -12.06

H-bond Donors 46.0

H-bond Acceptors 34.0

Rotatable Bonds 78.0

Heavy Atoms 159.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0264725 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer

TargetAcinetobacter baumannii ATCC 19606

Activity1-2 μM

MethodMIC

RECORD: Rec_0289658 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer

TargetCandida albicans ATCC 90028

Activity2 μM

MethodMIC

RECORD: Rec_0291346 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer Hemolytic

Targethuman red blood cells

RECORD: Rec_0307214 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer

TargetPseudomonas aeruginosa ATCC 27853

Activity0.25 μM

MethodMIC

RECORD: Rec_0326646 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer

TargetEscherichia coli ATCC 25922

Activity0.5-1 μM

MethodMIC

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