Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length237 amino acids

Chemical FormulaC1150H1765N289O341S12

DescriptionStandard

        TARIDDKIGIDYSLVAPPRATPKSLDLDLKGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHEAGALVFEITEAMIPKEAGFSLDTSIFSALIPQVSKNYPNMPMKFRLSTPTAPFLTIGQGGISFQPNVDIQAYAILPNSSLAPLFLLSLVSSDTACGDGAEGILSCAQSCCPDPVEFLQSIMNYLTSSVLLPHLNGENLLGERGCWSTPHSCCSIQGVPAH
    

Molecular Weight25479.83 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-9.12

Net Charge (pH 7.4) -9.76

Charge Density (pH 7.0) -0.0385

GRAVY Index0.15

Hydrophobic Moment 0.55

Boman Index0.19

Instability Index44.62

Aliphatic Index 88.57

Aromaticity 0.0970

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17795.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086205 VERIFIED: NO

Provenance & Taxonomy

OrganismGeospiza parvula (Small tree-finch) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria