Peptide Database

Peptide NameCrotamine

Function Ontology

—

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC213H333N63O52S7

DescriptionStandard

        YKRCHKKGGHCFPKEKICIPPSSDFGKMDCRWKWKCCKKGS
    

Molecular Weight4832.77 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)8.87

Net Charge (pH 7.4) 8.46

Charge Density (pH 7.0) 0.2163

GRAVY Index-1.10

Hydrophobic Moment 0.59

Boman Index-0.30

Instability Index64.33

Aliphatic Index 19.02

Aromaticity 0.1220

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1866.71

LogP -16.32

H-bond Donors 72.0

H-bond Acceptors 70.0

Rotatable Bonds 163.0

Heavy Atoms 335.0

Ring Count 12.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0189100 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus oreganus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)