Peptide Database

Peptide NameDisrupted colicin B activity protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC889H1400N244O272S5

DescriptionStandard

        MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSMPPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAARTVLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGNNVPVKYRLTDLMQNIWLLSEVFR
    

Molecular Weight20018.42 Da

Isoelectric Point (pI)4.81

Net Charge (pH 7.0)-6.38

Net Charge (pH 7.4) -6.68

Charge Density (pH 7.0) -0.0343

GRAVY Index-0.23

Hydrophobic Moment 0.64

Boman Index0.08

Instability Index51.47

Aliphatic Index 87.47

Aromaticity 0.0645

Extinction Coeff. Reduced 37470.00

Extinction Coeff. Oxidized 37470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8166.00

LogP -96.17

H-bond Donors 276.0

H-bond Acceptors 272.0

Rotatable Bonds 642.0

Heavy Atoms 1410.0

Ring Count 36.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120722 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli