Peptide Database

Peptide NameOral alpha defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC424H705N139O143S7

DescriptionStandard

        MRTLAILAAILLFTLLAQAKSLQERADDAATQEQPGEDDQDLAVSFEENGLSTLRDSGSQARRTCHCRSRCLRRESNSGSCNINGRIFSLCCR
    

Molecular Weight10262.43 Da

Isoelectric Point (pI)6.55

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.40

Hydrophobic Moment 0.67

Boman Index-0.17

Instability Index70.17

Aliphatic Index 80.97

Aromaticity 0.0323

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4649.28

LogP -61.73

H-bond Donors 171.0

H-bond Acceptors 151.0

Rotatable Bonds 353.0

Heavy Atoms 713.0

Ring Count 5.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076795 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence