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MYP_067424
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Basic Information
Defensin teta BTD-3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
18 amino acids
C82H136N30O21S6
Standard
Sequence
RCVCTRGFCRCVCTRGFC
Physicochemical Analysis
2070.54 Da
9.01
3.70
3.41
0.2056
0.49
0.62
-0.17
27.86
32.22
0.1111
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
846.08
-10.91
39.0
31.0
65.0
139.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0245205 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
2-11, 4-9, 13-18
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
At high physiological salt concentrations: Escherichia coli ML35p
2.2 μM
MIC
PMID20155756 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20155756/
RECORD: Rec_0273707 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0286441 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
2-11, 4-9, 13-18
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 33591
4.5 μM
MIC
PMID20155756 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20155756/
RECORD: Rec_0302544 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
2-11, 4-9, 13-18
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Listeria monocytogenes EGD
1.5 μM
MIC
PMID20155756 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20155756/
RECORD: Rec_0315997 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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