‹ ›
MYP_067409
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV cross
Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV ▸ Anti-HPIV3 cross
Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection
Standard
35 amino acids
C180H291N51O59
Standard
Sequence
PIDISIELNKAKSDLEESKEWIRRSNQKLDSIGNW
Physicochemical Analysis
4113.54 Da
5.10
-1.03
-1.10
-0.0295
-1.01
0.66
-0.23
64.01
92.00
0.0571
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1832.80
-18.45
64.0
58.0
145.0
290.0
5.0
38.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0085903 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0124464 VERIFIED: YES
Provenance & Taxonomy
Human parainfluenza virus 3 [Virus]
Virus-derived peptide
11216;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Human parainfluenza virus type 3 (Hemagglutinin-Neuraminidase)
Cell-fusion assay
PaperMethods and compositions for inhibition of membrane fusion-associated events | Shawn O'Lin, Dennis Michael, Stephen Robert | Trimeris, Inc., Durham NC (US) | Patent:US6951717 Evidence URLhttps://patents.google.com/patent/US6951717/en PatentUS6951717
RECORD: Rec_0125548 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US6228983B1/en PatentUS 6228983 B1
RECORD: Rec_0276802 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Respiratory syncytial virus fusion-inhibitory peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-Influenza Anti-RSV Anti-HPIV3 Fusion inhibitor
Human parainfluenza virus 3
PaperHuman respiratory syncytial virus peptides with antifusogenic and antiviral activities Evidence URLhttps://patents.google.com/patent/US6228983B1/en PatentUS 6228983 B1
RECORD: Rec_0328913 VERIFIED: YES
Provenance & Taxonomy
Human parainfluenza virus 3 [Virus]
Virus-derived peptide
11216;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor Cytoprotective
Human parainfluenza virus type 3 (Fusion); HEp2
0.07 μM
EC50
PaperPeptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion. | Lambert DM, Barney S, Lambert AL, Guthrie K, Medinas R, Davis DE, Bucy T, Erickson J, Merutka G, Petteway SR Jr. | Proc Natl Acad Sci U S A. 1996 | PMID:8700906 PMID8700906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8700906/
1 2 NEXT LAST
Showing 5 records · Page 1 of 2