Peptide Database

Peptide NameDefensin alpha 8

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length103 amino acids

Chemical FormulaC513H813N141O157S8

DescriptionStandard

        MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT
    

Molecular Weight11724.31 Da

Isoelectric Point (pI)5.16

Net Charge (pH 7.0)-4.35

Net Charge (pH 7.4) -4.79

Charge Density (pH 7.0) -0.0423

GRAVY Index-0.46

Hydrophobic Moment 0.81

Boman Index-0.06

Instability Index58.56

Aliphatic Index 75.83

Aromaticity 0.0680

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4809.59

LogP -45.47

H-bond Donors 167.0

H-bond Acceptors 163.0

Rotatable Bonds 394.0

Heavy Atoms 819.0

Ring Count 17.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056510 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence