Peptide Database

Peptide NameAvBD-12 [C5,12,17,27,34,35S][D3R,D8K,E21K,E29R]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC216H355N67O62

DescriptionStandard

        GPRSSNHKRGLSRVGNSNPGKYLAKYSFRPVILSSKPLSPTPTKT
    

Molecular Weight4882.54 Da

Isoelectric Point (pI)11.61

Net Charge (pH 7.0)8.84

Net Charge (pH 7.4) 8.58

Charge Density (pH 7.0) 0.1964

GRAVY Index-0.91

Hydrophobic Moment 0.65

Boman Index-0.20

Instability Index55.96

Aliphatic Index 58.44

Aromaticity 0.0667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2089.62

LogP -27.64

H-bond Donors 74.0

H-bond Acceptors 72.0

Rotatable Bonds 156.0

Heavy Atoms 345.0

Ring Count 10.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339586 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity16 μg/mL

MethodMBC

RECORD: Rec_0382490 VERIFIED: YES