Peptide Database

Peptide NameTurgencin A

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC157H269N45O43S7

DescriptionStandard

        GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV
    

Molecular Weight3699.55 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.1582

GRAVY Index-0.12

Hydrophobic Moment 0.53

Boman Index-0.02

Instability Index49.65

Aliphatic Index 54.44

Aromaticity 0.0278

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1403.25

LogP -14.38

H-bond Donors 54.0

H-bond Acceptors 56.0

Rotatable Bonds 126.0

Heavy Atoms 252.0

Ring Count 4.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415152 VERIFIED: YES

Provenance & Taxonomy

OrganismSynoicum turgens [Animal]

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Disulfide8-33, 12-29, 17-26

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer

TargetGram-positive bacteria: Bacillus megaterium

Activity0.5 μg/mL

MethodMIC

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