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MYP_067370
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Basic Information
Turgencin A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
36 amino acids
C157H269N45O43S7
Standard
Sequence
GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV
Physicochemical Analysis
3699.55 Da
9.24
5.70
5.39
0.1582
-0.12
0.53
-0.02
49.65
54.44
0.0278
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1403.25
-14.38
54.0
56.0
126.0
252.0
4.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0135381 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0140993 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0149589 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
8-33, 12-29, 17-26
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Micrococcus luteus
8 μg/mL
MIC
PMID32751755;31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751755/
RECORD: Rec_0214311 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
8-33, 12-29, 17-26
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Cancer:Human melanoma A2058
1.4 μM
IC50
PMID32751755;31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751755/
RECORD: Rec_0244522 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
8-33, 12-29, 17-26
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Pseudomonas aeruginosa
5.9 μg/mL
MIC
PMID32751755;31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751755/
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