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MYP_067370
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Basic Information
Turgencin A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
36 amino acids
C157H269N45O43S7
Standard
Sequence
GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV
Physicochemical Analysis
3699.55 Da
9.24
5.70
5.39
0.1582
-0.12
0.53
-0.02
49.65
54.44
0.0278
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1403.25
-14.38
54.0
56.0
126.0
252.0
4.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020333 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
the human melanoma cancer cell line A2058
1.4 μM
IC50
PaperIsolation and Characterization of Antimicrobial Peptides With Unusual Disulfide Connectivity From the Colonial Ascidian Synoicum turgens
RECORD: Rec_0033507 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Pseudomonas aeruginosa
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0036475 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0042899 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
8-33, 12-29, 17-26
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Bacillus subtilis
1.5 μg/mL
MIC
PMID32751755;31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751755/
RECORD: Rec_0063001 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
8-33, 12-29, 17-26
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Rhodotorula sp
23.2 μg/mL
MIC
PMID32751755;31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751755/
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