Peptide Database

Peptide Namefurin inhibitor peptide

Function Ontology

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC58H112N28O14

DescriptionStandard

        TPRARRRKKRT
    

Molecular Weight1425.69 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.40

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.5815

GRAVY Index-2.86

Hydrophobic Moment 0.45

Boman Index-1.36

Instability Index136.02

Aliphatic Index 9.09

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 747.53

LogP -9.89

H-bond Donors 30.0

H-bond Acceptors 21.0

Rotatable Bonds 50.0

Heavy Atoms 100.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255545 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-Termamidated

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Enzyme inhibitory

Targetfurin, paired basic amino acid cleaving enzyme (Human); proprotein convertase subtilisin/kexin type 4 (Human); proprotein convertase subtilisin/kexin type 5 (Human)

Activity23 nM

MethodKi