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MYP_067268
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Basic Information
Beta-lactorphin
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
4 amino acids
C30H42N4O6
Standard
Sequence
YLLF
Physicochemical Analysis
554.68 Da
5.52
-0.24
-0.45
-0.0602
2.27
0.12
0.89
7.50
195.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
170.85
2.14
6.0
6.0
15.0
40.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0342586 VERIFIED: YES
Provenance & Taxonomy
Acetes chinensis [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Osteoanabolic ACE inhibitory
Angiotensin-converting enzyme
172 μM
IC50
RECORD: Rec_0359135 VERIFIED: YES
Provenance & Taxonomy
Acetes chinensis [Animal]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
172 μM
IC50
PaperAnalysis of novel angiotensin-I-converting enzyme inhibitory peptides from protease-hydrolyzed marine shrimp Acetes chinensis PMID16981241 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16981241/
RECORD: Rec_0361948 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Opioid peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
RECORD: Rec_0377435 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Osteoanabolic Bone-protective
PaperEvaluation of the osteoprotective potential of whey derived-antioxidative (YVEEL) and angiotensin-converting enzyme inhibitory (YLLF) bioactive peptides in ovariectomised rat | Pandey, M. et al. | DOI: 10.1039/C8FO00620B Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
RECORD: Rec_0393843 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Osteoanabolic Bone-protective
Cell proliferation assay
PaperOsteoanabolic activity of whey-derived anti-oxidative (MHIRL and YVEEL) and angiotensin-converting enzyme inhibitory (YLLF, ALPMHIR, IPA and WLAHK) bioactive peptides | Pandey, M. et al. | DOI: 10.1016/j.peptides.2017.11.004 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
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