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MYP_067217
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Basic Information
CNP-29
Cardiovascular
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
29 amino acids
C128H216N38O37S3
Standard
Sequence
YKGGNKKGLSKGCFGLKLDRIGSMSGLGC
Physicochemical Analysis
2975.51 Da
9.79
4.74
4.49
0.1633
-0.29
0.45
-0.00
17.06
67.24
0.0690
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1231.43
-14.71
46.0
45.0
107.0
206.0
2.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0249423 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 24.1%, E 0.0%, T 55.2%, C 20.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0255356 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
CNP
9823
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
13-29
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PMID2139780 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2139780/
RECORD: Rec_0275672 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0327127 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
CNP
10090
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
13-29
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PMID11259675;12890708 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11259675/
RECORD: Rec_0352441 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
CNP
9913
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
13-29
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PMID8011167 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8011167/
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