Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC926H1476N256O255S8

DescriptionStandard

        PVTPPMAHEPMLLLAVTEFVANSAASTYFTAGALRRNISSDMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDSLHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELAQGLPVPQVKRLETLLKFGLWLFGVPQANSKCCPRAVP
    

Molecular Weight20531.71 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)5.30

Net Charge (pH 7.4) 4.97

Charge Density (pH 7.0) 0.0285

GRAVY Index-0.03

Hydrophobic Moment 0.57

Boman Index0.07

Instability Index58.29

Aliphatic Index 93.33

Aromaticity 0.0699

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8038.45

LogP -94.65

H-bond Donors 275.0

H-bond Acceptors 272.0

Rotatable Bonds 648.0

Heavy Atoms 1445.0

Ring Count 40.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413098 VERIFIED: NO

Provenance & Taxonomy

OrganismThryothorus ludovicianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria