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MYP_067133
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Basic Information
Ranatuerin-2Pb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C155H272N42O46S2
Standard
Sequence
SFLTTVKKLVTNLAALAGTVIDTIKCKVTGGCRT
Physicochemical Analysis
3524.20 Da
9.70
3.44
3.19
0.1011
0.59
0.56
0.17
-13.83
111.76
0.0294
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1431.83
-15.86
54.0
52.0
119.0
245.0
1.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0241125 VERIFIED: YES
Provenance & Taxonomy
Rana pipiens [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
8 μM
MIC
PMID31242693 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31242693/
RECORD: Rec_0245387 VERIFIED: YES
Provenance & Taxonomy
Rana pipiens [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus
32 μM
MBC
PMID31242693 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31242693/
RECORD: Rec_0255850 VERIFIED: YES
Provenance & Taxonomy
Rana pipiens [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
8 μM
MIC
PMID31242693 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31242693/
RECORD: Rec_0265461 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Cytotoxic
PaperBioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues PMID31242693 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31242693/
RECORD: Rec_0314122 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Enterococcus faecalis
256 μM
MIC
PaperBioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues PMID31242693 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31242693/
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