Peptide Database

Peptide NameLSEI_2135 (53-68), LHH1

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC89H139N27O18

DescriptionStandard

        AFALIAGALYRIFHRR
    

Molecular Weight1875.23 Da

Isoelectric Point (pI)11.71

Net Charge (pH 7.0)2.88

Net Charge (pH 7.4) 2.64

Charge Density (pH 7.0) 0.1801

GRAVY Index0.69

Hydrophobic Moment 0.69

Boman Index0.16

Instability Index29.30

Aliphatic Index 122.50

Aromaticity 0.1875

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 734.43

LogP -3.25

H-bond Donors 28.0

H-bond Acceptors 22.0

Rotatable Bonds 59.0

Heavy Atoms 134.0

Ring Count 4.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422683 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetMurine macrophage cells RAW 264.7

Activity0-10 %

MethodKilling

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