Peptide Database

Peptide NameCecropin-A (1-8)+Protegrin 1(1-16), CA-PG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC136H224N44O26S4

DescriptionStandard

        KWKLFKKIRGGRLCYCRRRFCVCV
    

Molecular Weight3019.77 Da

Isoelectric Point (pI)10.56

Net Charge (pH 7.0)8.72

Net Charge (pH 7.4) 8.45

Charge Density (pH 7.0) 0.3631

GRAVY Index-0.21

Hydrophobic Moment 0.37

Boman Index-0.31

Instability Index39.30

Aliphatic Index 72.92

Aromaticity 0.1667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1182.22

LogP -7.03

H-bond Donors 50.0

H-bond Acceptors 39.0

Rotatable Bonds 103.0

Heavy Atoms 210.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339221 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetSalmonella typhimurium CMCC 50013

Activity16 μg/mL

MethodMIC

RECORD: Rec_0406148 VERIFIED: YES