Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2392H3791N647O679S13

DescriptionStandard

        MGVRSLLVASTVLALGLALSGATNPGFVVRITQAGLDYAKQHGVAILEEELAQLKLQDISGESRIPVLGKVRYEISGLNLRDFQLPHSQISLVPNEGLQVSISNAFAELDGNWRVKLRILRHHGSFNLNVEHIYIKTILKLGRDDSGKPTVDISACSTSISNVRVHFSGKLSWLYNLFRKTIASKFKENLEDKVCETLRSSARRYLQPYLQTVPVTANIDAVAGIDYSLTAAPVATAQFLNVDLKGECFSLAQRTPVPFTPPALAVPPEHNRMVYFGVSSYFFNTASFAYHTAGALIFDITDAMIPKDIEFRLNTSTFAAFLPQLDEMYPNMPMKFRLSAPSAPFLNIGTNGVSLQPVVDIQAYAIYPNGNLAPLFLLGLTGNVSATTNVQSGRMVGSLAVGSMNLTLKHSNVGTGTFKVKMVQSIMNVVASSILLPRLNERLGKGFPLPLPAQVQLSDPIVQFHENFLLFGANVRYQPRRGR
    

Molecular Weight52893.46 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)10.38

Net Charge (pH 7.4) 9.52

Charge Density (pH 7.0) 0.0215

GRAVY Index0.10

Hydrophobic Moment 0.75

Boman Index0.12

Instability Index37.34

Aliphatic Index 100.93

Aromaticity 0.0870

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414021 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas platyrhynchos (Mallard) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria