Peptide Database

Peptide NameCathelicidin Cl-CATH3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC157H261N45O34

DescriptionStandard

        RVKRFWPLVPVAINTVAAGINLYKAIKRK
    

Molecular Weight3323.03 Da

Isoelectric Point (pI)11.75

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.2329

GRAVY Index0.18

Hydrophobic Moment 0.62

Boman Index0.03

Instability Index35.64

Aliphatic Index 121.03

Aromaticity 0.1034

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1292.75

LogP -7.10

H-bond Donors 46.0

H-bond Acceptors 41.0

Rotatable Bonds 108.0

Heavy Atoms 236.0

Ring Count 6.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0267835 VERIFIED: NO

Provenance & Taxonomy

OrganismColumba livia [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0419590 VERIFIED: YES

Provenance & Taxonomy

OrganismMeleagris gallopavo [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)