Peptide Database

Peptide NameNP-1 2b analog

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC157H275N65O36S2

DescriptionStandard

        VVGACRRALGLPRERRAGFCRIRGRIHPLGGRR
    

Molecular Weight3713.41 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.80

Net Charge (pH 7.4) 8.51

Charge Density (pH 7.0) 0.2668

GRAVY Index-0.46

Hydrophobic Moment 0.58

Boman Index-0.35

Instability Index77.52

Aliphatic Index 85.76

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1661.92

LogP -18.12

H-bond Donors 66.0

H-bond Acceptors 48.0

Rotatable Bonds 124.0

Heavy Atoms 260.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385112 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Toxicity

Targethuman RBC, not hemo.lytic

Activity3188 μg/mL

MethodHC50

RECORD: Rec_0412573 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans

Activity19.9 μg/mL

MethodMIC

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