Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length552 amino acids

Chemical FormulaC2639H4126N794O805S19

DescriptionStandard

        MGYRSTNYGRGQALHGDRTTTGAICCSTLPNCTEHGRGVIRVGDKTTACPKCGKQGVVADGEPRVNWMGQTSAVDGSVVICGCPHGTNRVIAPLGEWLGSGPSPEQIAQEKHQAMLAARRKEQEAEAQRQAEERDRNRVFAKSCLRGEGCNDAGTGSEPHTNFAEMAFYQAIPNNAPQHAQAAKRKALPKPKQRSALYLWWNGHHEEMDYQAAVAAEERAWTARTAIADASELALVGGRTITPGTWAVRGAALGEIATGGLGAPVAGLLIGMYPGKLNDGEQDFIDRMRAEQMREAPTRVRFTWENDASGNPTPRGWHTPPGKDSVRVRRMEWDSRRQAYTFTTEEAPGITLIWTPDRTGENKQWDTGNHNPVRIPNPVVVDPLPEDTGIGVTTSPTPEEKTFADYILILPVGGVPPIYVYIRHNPGQVTGKGQKISGIWLSDANVGNGSPIPSQIADRLRGQTFTDFDQFRKAFWLEVSREPVLLEQFIINNQSNIQSGASPFTPAIDKVGKRNRYEIHHINPISQGGAVYDLDNMSITTPKHHIDIHRGN
    

Molecular Weight60465.06 Da

Isoelectric Point (pI)7.26

Net Charge (pH 7.0)0.90

Net Charge (pH 7.4) -0.38

Charge Density (pH 7.0) 0.0016

GRAVY Index-0.60

Hydrophobic Moment 0.74

Boman Index-0.06

Instability Index40.24

Aliphatic Index 67.39

Aromaticity 0.0688

Extinction Coeff. Reduced 89380.00

Extinction Coeff. Oxidized 89880.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0233277 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter cloacae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)