Peptide Database

Peptide NameEclosion hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC305H475N73O87S8

DescriptionStandard

        NPAIATGYDPMEICIENCAQCKKMLGAWFEGPLCAESCIKFKGKLIPECEDFASIAPFLNKL
    

Molecular Weight6812.99 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-2.29

Net Charge (pH 7.4) -2.60

Charge Density (pH 7.0) -0.0369

GRAVY Index0.15

Hydrophobic Moment 0.49

Boman Index0.17

Instability Index45.19

Aliphatic Index 80.48

Aromaticity 0.0968

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2518.06

LogP -18.43

H-bond Donors 87.0

H-bond Acceptors 93.0

Rotatable Bonds 222.0

Heavy Atoms 473.0

Ring Count 12.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232383 VERIFIED: YES

Provenance & Taxonomy

OrganismManduca sexta [Animal]

FamilyEclosion hormone

Tax ID7130

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide14-38; 18-34; 21-49

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour