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MYP_066855
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Basic Information
Myotoxin II (105-117)[Y3,5,6W][P9A,C11A], PEM-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C87H136N24O14
Standard
Sequence
KKWRWWLKALAKK
Physicochemical Analysis
1742.16 Da
11.39
5.76
5.54
0.4427
-1.19
0.56
-0.33
56.25
75.38
0.2308
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
651.89
0.43
25.0
20.0
59.0
125.0
6.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0202133 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
5 % hemolysis at 64 μg/mL
Hemolysis
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0210619 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
50.0 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0219450 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
3.125 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0221656 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
3.125 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0225511 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida parapsilosis ATCC 22019
6.25 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
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