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MYP_066855
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Basic Information
Myotoxin II (105-117)[Y3,5,6W][P9A,C11A], PEM-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C87H136N24O14
Standard
Sequence
KKWRWWLKALAKK
Physicochemical Analysis
1742.16 Da
11.39
5.76
5.54
0.4427
-1.19
0.56
-0.33
56.25
75.38
0.2308
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
651.89
0.43
25.0
20.0
59.0
125.0
6.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0380167 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
12.5 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0395025 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
1.0 μg/mL
MBC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0402763 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Brucella abortus 45.20
250.0 μg/mL
MBC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0409193 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0411021 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida glabrata ATCC 9003
25.0 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
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