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MYP_066855
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Basic Information
Myotoxin II (105-117)[Y3,5,6W][P9A,C11A], PEM-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C87H136N24O14
Standard
Sequence
KKWRWWLKALAKK
Physicochemical Analysis
1742.16 Da
11.39
5.76
5.54
0.4427
-1.19
0.56
-0.33
56.25
75.38
0.2308
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
651.89
0.43
25.0
20.0
59.0
125.0
6.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005698 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
5.0 μg/mL
MBC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0017081 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida krusei ATCC 6258
12.5 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0027514 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii
5.3
MBC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0027657 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 19636
25.0 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0027772 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
6.3 μg/mL
MIC
PMID27591703;15793109;20865718;23896553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
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