Peptide Database

Peptide NameGranulocyte colony-stimulating factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length178 amino acids

Chemical FormulaC856H1360N226O249S8

DescriptionStandard

        ATPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLVSECATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP
    

Molecular Weight19057.84 Da

Isoelectric Point (pI)5.43

Net Charge (pH 7.0)-4.79

Net Charge (pH 7.4) -5.34

Charge Density (pH 7.0) -0.0269

GRAVY Index0.20

Hydrophobic Moment 0.71

Boman Index0.19

Instability Index63.36

Aliphatic Index 105.34

Aromaticity 0.0618

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7448.79

LogP -78.93

H-bond Donors 253.0

H-bond Acceptors 257.0

Rotatable Bonds 617.0

Heavy Atoms 1339.0

Ring Count 31.0

Amide Bonds 194.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394744 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-6 superfamily

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide40-46; 68-78

Bio-Activity Profile

Function

Cytokine Growth factor IL-6 superfamily